Thyroid nodules

By Dr. Meei Yeung (MBBS, FRACS)

What are thyroid nodules?

Thyroid nodules are lumps that form in the thyroid gland, which is located in the neck. They may be a solid or fluid-filled lump that forms in the thyroid gland which can be benign (noncancerous) or malignant (cancerous). They can also be functional (overactive) or non-functional (not overactive). Thyroid nodules are relatively common and are found in up to 50% of the population. However, most thyroid nodules are benign and do not cause any symptoms or require treatment. The discovery of thyroid nodules is often incidental, found during a routine physical examination or imaging study for another reason.

What causes thyroid nodules?

Thyroid nodules are a common condition of which the cause is yet unknown. They are more common in women than in men, and the frequency increases with age. According to some studies, about 5-7% of thyroid nodules are malignant.  These slow-growing lumps (millimeters over months or years) may be due to iodine deficiency as well as exposure in childhood to ionizing radiation – all without causing any symptoms most times.

How would I know if I have a thyroid nodule?

Most nodules in the thyroid do not cause any symptoms ie. patients are not aware that they have one. But when they reach a certain size, their location near the food pipe (oesophagus) and breathing tube (trachea), may lead to symptoms including a sensation of a lump in the throat and even difficulty swallowing or breathing. As mentioned earlier, if a nodule is overactive, it may be picked up on blood tests first and then confirmed with an ul;trsaound scan.  Another way in which thyroid nodules may be detected is incidentally – when tests are being done for another reason, but picks up an abnormality elsewhere.

Investigation of thyroid nodules

Once a nodule is detected it is best you go and see your general practitioner for further investigations. Common investigations include blood tests, an ultrasound scan of the thyroid and possibly a nuclear medicine scan of the thyroid gland. Depending on the appearance and size of the thyroid nodule, a fine needle aspiration biopsy (FNA or FNAB) of the nodule may be required. FNA of a thyroid nodule is one of the most important tests as it is getting cells from the nodule to help determine what the nodule is – benign or malignant (cancerous).

You May Also Like

What is nomocalcaemic primary hyperparathyroidism?

What does the Bethesda Category of thyroid nodule biopsies mean?

Are Radiological Studies Needed When Having Surgery for Primary Hyperparathyroidism?

© 2026 Dr Meei Yeung.
Thyroid Parathyroid Surgeon
Melbourne

Create a free website with Framer, the website builder loved by startups, designers and agencies.